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2025 Week Ten Picks
| Favorite | Line | Underdog | Trips Pick | Result |
 | 18.5 |  | | Ohio State 38 Penn State 14 |
 | 10.5 |  | | SMU 26 Miami (FL) 20 (OT) |
 | 12.5 |  | | Ole Miss 30 South Carolina 14 |
 | 4.5 |  | | USC 21 Nebraska 17 |
 | 10.5 |  | | Florida State 42 Wake Forest 7 |
 | 2.5 |  | | 49ers 34 Giants 24 |
 | 3.5 |  | | Steelers 27 Colts 20 |
 | 1.5 |  | | Broncos 18 Texans 15 |
 | 2.5 |  | | Bills 28 Chiefs 21 |