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2025 Week Six Picks
| Favorite | Line | Underdog | Trips Pick | Result |
 | 6.5 |  | | Pitt 48 Boston College 7 |
 | 4.5 |  | | Miami (FL) 28 Florida State 22 |
 | 1.5 |  | | Cincinnati 38 Iowa State 30 |
 | 5.5 |  |  | Florida 29 Texas 21 |
 | 11.5 |  | | Alabama 30 Vanderbilt 14 |
 | 1.5 |  | | Cowboys 37 Jets 22 |
 | 3.5 |  | | Buccaneers 38 Seahawks 35 |
 | 2.5 |  | | Commanders 27 Chargers 10 |
 | 4.5 |  | | Broncos 21 Eagles 17 |